位于非洲的神秘国家瓦坎达，凭借来自宇宙的振金而成为科技极度发达的国家，不过他们长久封闭，始终对外界保守这个秘密。在前国王死于联合国爆炸袭击后，特查拉王子（查德维克·博斯曼 Chadwick Boseman 饰）继任成为新的国王，同时他也是黑豹的继承者。登基之后，特查拉与前女友娜吉雅（露皮塔·尼永奥 Lupita Nyong'o 饰）、贴身侍卫奥姆烨（丹娜·奎里拉 Danai Gurira 饰）追查曾经盗取振金并杀害瓦坎达人的尤利西斯·克劳（安迪·瑟金斯 Andy Serkis 饰）。一番厮杀后，克劳侥幸逃脱，谁知最终死于合伙人艾瑞克·克尔芒戈（迈克尔·B·乔丹 Michael B. Jordan 饰）之手。艾瑞克同样具有瓦坎达血统，而且当年他的父亲死在了自己的兄弟——特查拉父亲的手中。 　　怀着莫大的仇恨，艾瑞克踏足瓦坎达，去争夺至高无上的王位……After the events of Captain America: Civil War, King T'Challa returns home to the reclusive, technologically advanced African nation of Wakanda to serve as his country's new leader. However, T'Challa soon finds that he is challenged for the throne from factions within his own country. When two foes conspire to destroy Wakanda, the hero known as Black Panther must team up with C.I.A. agent Everett K. Ross and members of the Dora Milaje, Wakandan special forces, to prevent Wakanda from being dragged into a world war.